Given the continuous evolution of the virus that leads to SARS-CoV-2 and the constant developments in our understanding of the impacts of variants, these working definitions may be periodically adjusted. When necessary, variants not otherwise meeting all criteria outlined in these definitions may be designated as VOIs/VOCs, and those posing a diminishing risk relative to other circulating variants may be reclassified, in consultation with the WHO Technical Advisory Group on Viral Evolution.

The mutation of the corona virus continues to grow. In table 1, it can be seen that the variant that is of concern to the public and the world or WHO calls it Variant of concern. In the midst of concerns about the Delta variant, which was last included in its list, this time the World Health Organization (WHO) has again listed one new coronavirus variant, the Mu variant, in the Variant of Interest (VOI) list. Some of the variants discussed are shown in table 2

The Mu variant is a coronavirus variant that was first identified in Colombia. Here’s what you need to know about the Covid Mu variant, which WHO has started monitoring since the end of August 2021

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Corona variant that is immune to vaccines

The variant of the Mu corona that was found to have a group of mutations that might make it less susceptible to the immune protection produced by the Covid-19 vaccine. it has a constellation of mutations that exhibit the potential for escaping immunity. This means that this variant of the new corona virus has the potential to be immune to the Covid-19 vaccine. Preliminary data suggest this new variant of the coronavirus may be able to evade immune system defenses in a similar way to the Beta variant.
some of the people who have tested positive for the Mu variant of Covid, have received a dose or two of the Covid-19 vaccine.

Such as genetic changes from several mutations of the corona virus carried by the Alpha variant and the Delta variant. One genetic change, the P681H mutation, was found in the Alpha variant which was first detected in Kent, England and has been associated with faster transmission. Other mutations, including E484K and K417N, may help the virus evade immune defenses, which could give the variant an edge over the Delta variant as immunity increases into the fall.

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in table 3 is A SARS-CoV-2 variant with genetic changes that are suspected to affect virus characteristics with some indication that it may pose a future risk, but evidence of phenotypic or epidemiological impact is currently unclear, requiring enhanced monitoring and repeat assessment pending new evidence.



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